Associate Scientist II - Contract - Lexington, MA
Be the backbone of innovation and join a leading pharmaceutical company to help keep life-changing science moving forward!
À±½·ÊÓƵ is seeking a motivated Associate Scientist II to join the Oligonucleotide Chemistry Team at our client's facility.
Primary Responsibilities:
The successful candidate will focus on the analysis and purification of oligonucleotides, supporting therapeutic programs across various disease areas. Your expertise in LC/MS method development and oligonucleotide purification will be crucial in advancing novel nucleic acid conjugate platforms.
Skills & Requirements:
- Proficiency in mass spectrometry and purification techniques.
- Experience with waters LC/MS instruments and sgRNA analysis preferred.
- Familiarity with analytical techniques such as RP-UPLC, SAX-HPLC, LC-MS, and data interpretation.
- Background in developing analytical methods for oligonucleotide therapeutics.
- Knowledge of IP-RP-UHPLC and AX-HPLC techniques using Agilent, Waters, or Thermo UHPLCs.
- Understanding of GLP/GMPs in a pharmaceutical setting.
- Strong written and verbal communication skills, with the ability to work independently and collaboratively.
The Associate Scientist II's responsibilities will be:
- Provide analytical lab support for the early phase pipeline of oligonucleotides.
- Develop robust analytical methods using LC/MS, IPRP, and SAX for drug substance analysis and purification.
- Prepare samples, analyze data primarily using UPLC and LC-MS, and maintain accurate records.
- Operate, maintain, and troubleshoot laboratory instruments.
- Design and conduct experiments for characterizing modified oligonucleotides and sgRNA.
- Purify, deprotect, anneal, and lyophilize oligonucleotides to support disease programs.
- Synthesize oligonucleotides and ensure a safe working environment.
If you are having difficulty in applying or if you have any questions, please contact Jackie Cerchio at j.cerchio@proclinical.com
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
À±½·ÊÓƵ is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. À±½·ÊÓƵ is acting as an Employment Agency in relation to this vacancy.
By submitting this application, you confirm that you've read and understood our privacy policy, which informs you how we process and safeguard your data - /privacy-policy
