DMPK Research Associate - Contract - San Diego, CA
Ready to be the heartbeat of medical research? Join our client as a Research Associate and assist in turning innovative science into life-changing care!
À±½·ÊÓƵ is seeking a dedicated DMPK Research Associate to support the progression of our therapeutic programs.
Primary Responsibilities:
The successful candidate will be required to conduct routine bioanalysis of small molecules, antisense oligonucleotides (ASOs), and proteins for preclinical PK and PK/pharmacodynamic (PD) studies. This role demands a solid understanding of analytical principles, hands-on experience with targeted liquid chromatography (LC)-mass spectrometry (MS), and familiarity with DMPK fundamentals.
Skills & Requirements:
- Bachelor's or Master's degree in Chemistry, Biology, Pharmaceutical Sciences, or related field, and 1-3 years of experience in bioanalysis.
- Possesses direct hands-on experience with bioanalysis and absolute quantitation with LC-MS and can perform basic method troubleshooting and optimization
- Possesses direct hands-on experience with non-LC-MS methods such as protein gels, Western blot, ELISA/MSD, and UV-vis.
- Has a firm understanding of analytical principles and can use figures of merit to evaluate data quality
- Experience performing bioanalysis on small molecules and proteins is desirable.
- Knowledge and experience using R-Studio, or similar platforms, for data analysis is desirable
The DMPK Research Associate's responsibilities will be:
- Conduct routine bioanalysis of drugs, metabolites, and PD markers in complex biological matrices such as biofluids, tissues, and cells
- Perform absolute quantitation on a triple quadrupole LC-MS system and calculations for non-compartmental analysis (NCA)
- Collaborate with DMPK and pharmacology leads on timeline planning, study prep, and experimental logistics
- Collect and record experimental data in an electronic lab notebook, ensuring meticulous documentation, data integrity, traceability, and regulatory compliance; produce readable and functional reports for PK data
- Contribute to the development and optimization of experimental techniques and protocols to ensure we deliver high-quality data for decision-making
- Monitor consumable inventory and provide basic troubleshooting, maintenance, and performance benchmarking for DMPK LC-MS systems
- Collaborate with cross-functional teams to support the development and progression of therapeutic programs
- Foster a team culture of continuous improvement, ownership, professional growth, and inclusion
Compensation:
If you are having difficulty in applying or if you have any questions, please contact Shannon Briggs at s.brigggs@proclinical.com
If you are interested in applying to this exciting opportunity, then please click 'Apply' or to speak to one of our specialists please request a call back at the top of this page.
À±½·ÊÓƵ is a leading life sciences recruiter focused on finding exceptional people and matching them with the finest positions across the globe. À±½·ÊÓƵ is acting as an Employment Agency in relation to this vacancy.
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